Services and Products Offered

Lego® Like Modular Microfluidics Platform: This platform allows the end user to assemble unique microfluidic devices from individual modules onto a platform that aligns the microfluidic channels. To market our modular microfluidic platform to potential customers, we will first reach out to researchers at the University of California Irvine as we develop an initial library of microfluidic modules.  Since our microfluidic modules are designed to be inexpensive, we intend to sell individual blocks for less than $1 allowing for them to be cheap enough to be considered disposable.  Therefore as we develop our customer base, there will always be demand for replacement microfluidic modules and for new ones as our library of designs expands.   This expanding library of designs will be made available to consumers via an online store listing the different designs, similar to Dolomite. Although this platform requires the end user to assemble the device using individual building blocks, the design of the platform is setup to make it as intuitive and simple as possible.  Since assembling blocks will be very similar to assembling Lego® pieces, it will be easy for new users unfamiliar with microfluidics to understand and use.  This may make potential users more open to the possibilities of microfluidics, especially as more designs are added to the library of designs. Lego Sandwich Platform: Through conversations with potential customers who were not actively using microfluidic devices it was found that many people weren’t interested in assembling their own devices, even if the process was simple and intuitive.  However, they were interested in the reversible sealing and inexpensive aspects of our platform.  Therefore we developed a Lego® sandwich platform that allows for rapid production of microfluidic devices using laser cutting technology that seals the device using pressure with a PDMS layer in the middle.  This method allows for inexpensive and rapid production of custom microfluidic devices without the use of adhesives. Accessories: We are currently developing a hydrostatic pressure reservoir system that will interface with both of our microfluidic platforms.  This will allow for long term, low pressure fluid flow through our microfluidic devices for specialized applications.  It will be designed to have sensors monitoring fluid level and flow rates to ensure proper functioning.  Additionally we are discussing the best way to integrate a user friendly method of attaching tubing to our microfluidic chips and modules. Future Developments 1. Fabricate more complex building blocks and expand library of designs 2. Optimize efficacy and repeatability 3. Determine leakage pressure 4. Application to cell studies 5. Mass production 6. Develop finalized Lego® Sandwich fabrication design Regulatory Strategy To ensure our devices meet the specific needs of customers we intend to produce our microfluidic products using materials that are non-reactive and already have a strong or growing presence in the microfluidic market.  These materials include, but are not limited to PDMS, PMMA, and COC. PDMS (poly-di-methyl-siloxane) has been used in microfluidics for decades due to its optical transparency, bio- compatibility, and its ability to deform.  PMMA (poly-methyl-methacrylate) is a growing microfluidic material due to its low cost, excellent optical transparency and being non-reactive with many chemicals.  COC (cyclic-olefin-copolymer) is a relatively new polymer that is growing in microfluidic applications due to its exceptional optical transparency, high ultraviolet transmission, and resistance to solvents such as alcohols and resistance to acids/bases.^2,3 Since we intend to develop designs for cell culturing, biocompatibility is an important aspect to consider.  By using PDMS, which is a well understood material that is compatible with cell growth, the individual modules will exhibit a degree of gas permeability.  This permeability could potentially allow for incubation of cells without a direct port allowing for air.  This aspect will need to be researched further and testing will need to be performed to assess the validity of incubating cells in this manner with our platform. In accordance with the procedures of other microfluidic companies, we will seek to ensure a quality management system according to    ISO 9001: 2015. ISO 9001:2015    “Specifies requirements for a quality management system when an organization: needs to demonstrate its ability to consistently provide products and services that meet customer and applicable statutory and regulatory requirements, and aims to enhance customer satisfaction through the effective application of the system, including processes for improvement of the system and the assurance of conformity to customer and applicable statutory and regulatory requirements.” (iso.org)

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